Alzheimer Treatment (Genetics)

Alzheimer's disease, the majority of the cases are sporadic, meaning that there is no genetic basis, while some genes can have gained by risk factors. On the other hand is about 0.1% of the cases (path) is the dominant autosomno the familiar forms of the world cultural heritage of UNESCO, after 65 years. This form of the disease, early-onset Alzheimer's disease is known as a family.

The most dominant autosomno AD explaining one of the families of the three genes mutation: (APP), presenilins 1 and 2 and amyloid precursor protein. Most of the mutations of genes, presenilin protein APP and a small increase of Aβ42 which exit is an important component of senile plaques. Some mutations can change, it is part of other serious forms of Aβ42 and, for example, without an increase in levels of Aβ42 Aβ40. This shows that presenilin mutations can cause disease, and reduce the Aβ can refer to another role or roles you want to change the functions of presenilin programmes and that the total amount of Aβ fragments.

In most cases, Alzheimer's disease, or non-transmission of the dominant autosomno, and Iceland, sporadic ads display name. However, genetic differences, can function as risk factors. Known genetic risk factor, the legacy of apolipoprotein E (APOE) were the alelo example described. 80% of the population has less advertising APOEε4 is 40. Increases the disease allele APOEε4 homozygotes and heterozygoti at up to three times. Note that this is not necessarily the full effect "Genetics" genetics. For example, some people in Nigeria, and the presence or not of the morbidity of APOEε4 and portion or the relationship between the age of Alzheimer's disease. List of biokémikusok and agree that there are many other genes also act as risk factors or protective influence on Alzheimer's disease, but a new version of the results, the development of the Nigerian state and the lack of any genetic, sporadic Alzheimer's disease risk factors showed strong position on the impact on the environment. More than 400 genes have been tested at the end of my sporadic e vacuum results.